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CRYAB 抗体

CRYAB 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5965510
发货至: 中国
  • 抗原 See all CRYAB 抗体
    CRYAB (Crystallin, alpha B (CRYAB))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 155
    • 29
    • 2
    • 1
    克隆类型
    • 150
    • 37
    多克隆
    标记
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    This CRYAB antibody is un-conjugated
    应用范围
    • 132
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    Western Blotting (WB)
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human CRYAB
    亚型
    IgG
    Top Product
    Discover our top product CRYAB Primary Antibody
  • 应用备注
    WB 1:500 - 1:2000
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CRYAB (Crystallin, alpha B (CRYAB))
    别名
    Crystallin-alpha B (CRYAB 产品)
    别名
    CMD1II antibody, CRYA2 antibody, CTPP2 antibody, CTRCT16 antibody, HSPB5 antibody, MFM2 antibody, Crya-2 antibody, Crya2 antibody, HspB5 antibody, AACRYA antibody, CRYAB antibody, cryab antibody, cryab2 antibody, wu:fe37f08 antibody, zgc:91937 antibody, crystallin alpha B antibody, crystallin, alpha B antibody, hypothetical protein antibody, crystallin, alpha B, a antibody, crystallin, alpha B, b antibody, CRYAB antibody, Cryab antibody, ZK1128.7 antibody, cryaba antibody, cryabb antibody
    背景

    Synonyms: AACRYA,Alpha B crystallin,Alpha crystallin B chain,Alpha(B)-crystallin,Alpha-crystallin B chain,CRYA2,Cryab,CRYAB,Crystallin alpha B,Crystallin alpha polypeptide 2,CTPP2,Heat shock 20 kD like protein,Heat shock protein beta 5,Heat shock protein beta-5,HspB5,Renal carcinoma antigen NY REN 27,Renal carcinoma antigen NY-REN-27,Rosenthal fiber component

    Background: Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits, the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Alpha-A and alpha-B gene products are differentially expressed, alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases, a missense mutation cosegregated in a family with a desmin-related myopathy. Alternative splicing results in multiple transcript variants.

    分子量

    Observed_MW: 20kDa

    Calculated_MW: 20kDa

    基因ID
    1410
    UniProt
    P02511
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