IRAK4 抗体 (N-Term)
Quick Overview for IRAK4 抗体 (N-Term) (ABIN656802)
抗原
See all IRAK4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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                                            抗原表位
- AA 25-52, N-Term
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                                            预测反应
- B, M
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                                            纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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                                            免疫原
- This IRAK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-52 amino acids from the N-terminal region of human IRAK4.
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                                            亚型
- Ig Fraction
 
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                                            应用备注
- WB: 1:1000. WB: 1:1000
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- 4 °C,-20 °C
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                                            储存方法
- IRAK4 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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                                            有效期
- 6 months
 
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    - 
                                            : "The anti-inflammatory effect and potential mechanism of cardamonin in DSS-induced colitis."    in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 309, Issue 7, pp. G517-27, (2015)         (PubMed).        
 
 
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                                            : "The anti-inflammatory effect and potential mechanism of cardamonin in DSS-induced colitis."    in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 309, Issue 7, pp. G517-27, (2015)         (PubMed).        
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    - IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
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                                            别名
- IRAK4
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                                            背景
- This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
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                                            分子量
- 51530
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                                            基因ID
- 51135
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                                            NCBI登录号
- NP_001107654, NP_001138728, NP_001138729, NP_001138730, NP_057207
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                                            UniProt
- Q9NWZ3
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                                            途径
- NF-kappaB Signaling, TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
 抗原
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