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DCC 抗体 (AA 643-670)

This anti-DCC antibody is a 兔 多克隆 antibody detecting DCC in WB 和 IHC (p). Suitable for 小鼠.
产品编号 ABIN656268
发货至: 中国

Quick Overview for DCC 抗体 (AA 643-670) (ABIN656268)

抗原

See all DCC 抗体
DCC (Deleted in Colorectal Carcinoma (DCC))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This DCC antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB32203
  • 抗原表位

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    AA 643-670

    预测反应

    Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This DCC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 643-670 amino acids from the Central region of human DCC.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    DCC Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    有效期

    6 months
  • 抗原

    DCC (Deleted in Colorectal Carcinoma (DCC))

    别名

    DCC

    背景

    This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.

    分子量

    158457

    基因ID

    1630

    NCBI登录号

    NP_005206

    UniProt

    P43146

    途径

    Regulation of Cell Size
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