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DDR1 抗体

DDR1 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal 51D6 unconjugated
产品编号 ABIN6559822
发货至: 中国
  • 抗原 See all DDR1 抗体
    DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This DDR1 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunoprecipitation (IP)
    原理
    Anti-Hu CD167a Purified
    特异性
    The mouse monoclonal antibody 51D6 recognizes an extracellular epitope of CD167a, an approximately 97-101 kDa receptor tyrosine kinase expressed mainly on epithelial cells, but also on B cells and dendritic cells.
    交叉反应 (详细)
    Human
    纯化方法
    Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    CD167a-transfected NIH-3T3 cells
    克隆位点
    51D6
    亚型
    IgM
    Top Product
    Discover our top product DDR1 Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • 抗原
    DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
    别名
    CD167a (DDR1 产品)
    背景
    Discoidin domain receptor tyrosine kinase 1,CD167a, also known as e.g. discoidin domain receptor tyrosine kinase 1 (DDR1), tyrosine kinase receptor E (TRKE), cell adhesion kinase (CAK), or neuroepithelial tyrosine kinase 4 (NEP, NTRK4), is a transmembrane receptor tyrosine kinase expressed predominantly in epithelial cells. It has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms of this protein have been described. After binding to fibrilar collagens I, II, III, V, or basement membrane collagens IV and VIII, CD167a becomes activated and autophosphorylated and transduces collagen-induced signaling.,EDDR1, MCK10, NTRK4, PTK3A, RTK6, CAK, TRKE, DDR1
    基因ID
    780
    UniProt
    Q08345
    途径
    RTK signaling, Smooth Muscle Cell Migration
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