STARD6 抗体 (C-Term)
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- 抗原 See all STARD6 抗体
- STARD6 (StAR-Related Lipid Transfer (START) Domain Containing 6 (STARD6))
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抗原表位
- AA 187-215, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This STARD6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This STARD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-215 amino acids from the C-terminal region of human STARD6.
- 克隆位点
- RB29820
- 亚型
- Ig Fraction
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- 应用备注
- WB: 1:1000. FC: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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STARD6 is expressed in steroidogenic cells of the ovary and can enhance de novo steroidogenesis." in: Experimental biology and medicine (Maywood, N.J.), Vol. 239, Issue 4, pp. 430-5, (2014) (PubMed).
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STARD6 is expressed in steroidogenic cells of the ovary and can enhance de novo steroidogenesis." in: Experimental biology and medicine (Maywood, N.J.), Vol. 239, Issue 4, pp. 430-5, (2014) (PubMed).
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- 抗原
- STARD6 (StAR-Related Lipid Transfer (START) Domain Containing 6 (STARD6))
- 别名
- STARD6 (STARD6 产品)
- 别名
- 1700011K09Rik antibody, 4833424I06Rik antibody, 4933429L05Rik antibody, AI644424 antibody, StAR related lipid transfer domain containing 6 antibody, StAR-related lipid transfer (START) domain containing 6 antibody, STARD6 antibody, Stard6 antibody
- 背景
- Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1, MIM 184756) and by liver X receptors (e.g., LXRA, MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR, MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD6 (Soccio et al., 2002 [PubMed 12011452]).
- 基因ID
- 147323
- NCBI登录号
- NP_631910
- UniProt
- P59095
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