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GAD65 抗体 (AA 109-138)

Name: GAD65 抗体 (AA 109-138)
SKU: ABIN655070
Availability: OutOfStock

GAD2 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB19330 unconjugated

GAD2 Antibody (Center) (ABIN655070 and ABIN2844700) western blot analysis in Jurkat cell line lysates (35 μg/lane). (GAD65 抗体 (AA 109-138))

GAD2 Antibody (Center) (ABIN655070 and ABIN2844700) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. (GAD65 抗体 (AA 109-138))

IHC (p)

Confocal immunofluorescent analysis of GAD2 Antibody (Center) (ABIN655070 and ABIN2844700) with 293 cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). (GAD65 抗体 (AA 109-138))

Western blot analysis of lysate from rat brain tissue lysate, using GAD2 Antibody (Center) (ABIN655070 and ABIN2844700). (GAD65 抗体 (AA 109-138))

4 images

(1 reference)

产品编号 ABIN655070

发货至: 中国

Datasheet as PDF

抗原 See all GAD65 (GAD2) 抗体

GAD65 (GAD2) (Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
抗原表位
16

10

7

7

7

7

6

6

6

5

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 109-138
适用
92

67

40

16

1

1

1

1
人
宿主
91

26

1
兔
Compatible Secondaries
克隆类型
94

24
多克隆
标记
60

13

12

6

3

2

2

2

2

2

2

2

2

2

2

2

2
This GAD65 antibody is un-conjugated
应用范围
100

43

40

20

17

17

13

13

13

12

3

3

2

1

1

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

预测反应

M, Pig, Rat

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This GAD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the Central region of human GAD2.

克隆位点

RB19330

亚型

Ig Fraction

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anti-Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) (AA 401-585) antibody
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anti-Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) (Internal Region) antibody
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anti-Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) (C-Term) antibody
GAD2 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) (AA 1-100) antibody
GAD2 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 5D9G12 unconjugated

anti-Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) (AA 131-164), (N-Term) antibody
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anti-Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) (AA 501-585) antibody
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anti-Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) (AA 1-82) antibody
GAD2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Jewett, Christian, Bacos, Lee, Zhu, Tsai: "Feedback modulation of neural network synchrony and seizure susceptibility by Mdm2-p53-Nedd4-2 signaling." in: Molecular brain, Vol. 9, pp. 32, (2016) (PubMed).
抗原

GAD65 (GAD2) (Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))

别名

GAD2 (GAD2 产品)

别名

GAD65 antibody, gad65 antibody, F12P19.12 antibody, F12P19_12 antibody, GLUTAMATE DECARBOXYLASE 2 antibody, glutamate decarboxylase 2 antibody, zgc:112198 antibody, 6330404F12Rik antibody, GAD(65) antibody, Gad-2 antibody, glutamate decarboxylase 2 antibody, glutamate decarboxylase 1 antibody, glutamic acid decarboxylase 2 antibody, GAD2 antibody, PTRG_06148 antibody, LOC9324534 antibody, Gad2 antibody, GAD1 antibody, gad2 antibody

背景

This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.

分子量

65411

基因ID

2572

NCBI登录号

NP_000809, NP_001127838

UniProt

Q05329