INSIG1 抗体 (N-Term)
Quick Overview for INSIG1 抗体 (N-Term) (ABIN652887)
抗原
See all INSIG1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 36-63, N-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This INSIG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-63 amino acids from the N-terminal region of human INSIG1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- INSIG1 (Insulin Induced Gene 1 (INSIG1))
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别名
- INSIG1
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背景
- INSIG1 is an insulin-induced protein. This protein encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. This protein binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins.
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分子量
- 29987
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基因ID
- 3638
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NCBI登录号
- NP_005533, NP_938150, NP_938151
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UniProt
- O15503
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途径
- ER-Nucleus Signaling
抗原
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