INSIG1 抗体 (N-Term)
INSIG1
适用: 人
WB, FACS, IHC (p)
宿主: 兔
Polyclonal
RB21689
unconjugated
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- 抗原 See all INSIG1 抗体
- INSIG1 (Insulin Induced Gene 1 (INSIG1))
- 抗原表位
- AA 36-63, N-Term
- 适用
- 人
- 宿主
- 兔
- 克隆类型
- 多克隆
- 应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This INSIG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-63 amino acids from the N-terminal region of human INSIG1.
- 克隆位点
- RB21689
- 亚型
- Ig Fraction
-
- 应用备注
- WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
-
- 抗原
- INSIG1 (Insulin Induced Gene 1 (INSIG1))
- 别名
- INSIG1
- 背景
- INSIG1 is an insulin-induced protein. This protein encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. This protein binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins.
- 分子量
- 29987
- 基因ID
- 3638
- NCBI登录号
- NP_005533, NP_938150, NP_938151
- UniProt
- O15503
- 途径
- ER-Nucleus Signaling
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