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POLR3H 抗体 (N-Term)

POLR3H 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB24730 unconjugated
产品编号 ABIN651129
发货至: 中国
  • 抗原 See all POLR3H 抗体
    POLR3H (Polymerase (RNA) III (DNA Directed) Polypeptide H (22.9kD) (POLR3H))
    抗原表位
    • 7
    • 6
    • 6
    • 5
    • 1
    • 1
    AA 5-33, N-Term
    适用
    • 27
    • 20
    • 13
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠
    宿主
    • 27
    克隆类型
    • 27
    多克隆
    标记
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This POLR3H antibody is un-conjugated
    应用范围
    • 20
    • 16
    • 12
    • 3
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This RPC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 5-33 amino acids from the N-terminal region of human RPC8.
    克隆位点
    RB24730
    亚型
    Ig Fraction
    Top Product
    Discover our top product POLR3H Primary Antibody
  • 应用备注
    WB: 1:1000. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    POLR3H (Polymerase (RNA) III (DNA Directed) Polypeptide H (22.9kD) (POLR3H))
    别名
    RPC8 (POLR3H 产品)
    别名
    5031409G22Rik antibody, RPC8 antibody, RPC22.9 antibody, polymerase (RNA) III (DNA directed) polypeptide H antibody, RNA polymerase III subunit H antibody, Polr3h antibody, POLR3H antibody
    背景
    RPC8 is DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. It is plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. It is acting as nuclear and cytosolic DNA sensor involved in innate immune response. It can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway.
    分子量
    22918
    基因ID
    171568
    NCBI登录号
    NP_001018060, NP_001018062, NP_612211
    UniProt
    Q9Y535
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