KAP1 抗体
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北京 101111
Quick Overview for KAP1 抗体 (ABIN645876)
抗原
See all KAP1 (TRIM28) 抗体适用
宿主
标记
应用范围
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特异性
- The Goat anti-KAP1 / TRIM28 antibody detects protein derived from human recombinant protein and HepG2 lysate at various concentrations.
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交叉反应
- 人, 小鼠
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产品特性
- Goat Anti-KAP1 / TRIM28
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免疫原
- Peptide with sequence C-SSQELSGGPGDGP, from the C Terminus of the protein sequence according to NP_005753, was used as an immunogen.
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亚型
- IgG
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anti-Tripartite Motif Containing 28 (TRIM28) (AA 379-524) antibody
TRIM28 适用: 人 WB, ELISA, IF, IHC (p), RNAi 宿主: 小鼠 Monoclonal 4E6 unconjugated
anti-Tripartite Motif Containing 28 (TRIM28) (C-Term) antibodyVerified TRIM28 适用: 人 IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Tripartite Motif Containing 28 (TRIM28) (AA 576-835) antibodyTRIM28 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 28 (TRIM28) (N-Term) antibodyTRIM28 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 28 (TRIM28) antibodyTRIM28 适用: 人 WB, IF, IP, ICC, IHC (p), ChIP 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 28 (TRIM28) (AA 379-524) antibodyTRIM28 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1D11 unconjugated
anti-Tripartite Motif Containing 28 (TRIM28) (pSer824) antibodyTRIM28 适用: 人, 小鼠 WB, IHC, IP, FACS, IF/ICC 宿主: 兔 Monoclonal BL-246-7B5 unconjugated Recombinant Antibody
anti-Tripartite Motif Containing 28 (TRIM28) (Ser824) antibodyTRIM28 适用: 人, 小鼠 WB, IHC, IP, FACS, ICC 宿主: 兔 Monoclonal BL-248-2G6 unconjugated Recombinant Antibody
anti-Tripartite Motif Containing 28 (TRIM28) (pSer824) antibodyTRIM28 适用: 人, 小鼠 WB, IP, ICC, IF/ICC, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 28 (TRIM28) (AA 699-835) antibodyTRIM28 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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溶解方式
- Supplied as 100µg of purified antibody. 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Please avoid freeze-thaw cycles.
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储存条件
- -20 °C
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- KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))
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别名
- KAP1 / TRIM28
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背景
- KAP1 is an 835 amino acid polypeptide that contains a RING finger, B boxes, and a PHD finger. KAP1 has been shown to form complexes with KRAB domain transcription factors and increase the efficiency with which they mediate repression. KAP1 has also been shown to directly interact with HP1 (heterochromatin protein 1) and KRAZ1 (Kruppel associated box containing zinc finger protein 1). KAP1 directly targets KRAZ1 to the foci of centromeric heterochromatin containing HP1alpha, helping to regulate transcriptional repression. Recent studies have shown that KAP1 mutants with the ability to bind KRAB but unable to bind HP1 leads to random distribution of KRAZ1 and strong transcriptional activation.
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NCBI登录号
- NP_005753
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途径
- Hedgehog Signaling, Positive Regulation of Response to DNA Damage Stimulus
抗原
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