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KAP1 抗体 (AA 699-835)

TRIM28 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043491
发货至: 中国
  • 抗原 See all KAP1 (TRIM28) 抗体
    KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))
    抗原表位
    • 29
    • 15
    • 11
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    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 699-835
    适用
    • 112
    • 52
    • 48
    • 10
    • 9
    • 8
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 113
    • 15
    • 4
    克隆类型
    • 107
    • 25
    多克隆
    标记
    • 61
    • 10
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This KAP1 antibody is un-conjugated
    应用范围
    • 84
    • 41
    • 41
    • 27
    • 26
    • 23
    • 21
    • 20
    • 19
    • 15
    • 6
    • 4
    • 4
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    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Transcription intermediary factor 1-beta(TRIM28) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Transcription intermediary factor 1-beta(TRIM28) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: tripartite motif containing 28
    Protein Name: Transcription intermediary factor 1-beta
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human KAP1 recombinant protein (Position: A699-P835). Human KAP1 shares 94.9% amino acid (aa) sequence identity with both mouse and rat KAP1.
    亚型
    IgG
    Top Product
    Discover our top product TRIM28 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))
    别名
    TRIM28 (TRIM28 产品)
    别名
    KAP1 antibody, RNF96 antibody, TF1B antibody, TIF1B antibody, TRIM28 antibody, kap1 antibody, rnf96 antibody, tf1b antibody, tif1b antibody, AA408787 antibody, KAP-1 antibody, KRIP-1 antibody, Tif1b antibody, Tif1beta antibody, Kap1 antibody, Krip1 antibody, TIF1BETA antibody, tripartite motif containing 28 antibody, tripartite motif containing 28 L homeolog antibody, tripartite motif-containing 28 antibody, TRIM28 antibody, trim28.L antibody, Trim28 antibody
    背景
    Tripartite motif-containing 28 (TRIM28), also known as transcriptional intermediary factor 1β (TIF1β) and KAP1 (KRAB-associated protein-1), is a protein that in humans is encoded by the TRIM28 gene. The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. KAP1 is a ubiquitously expressed protein involved in many critical functions including: transcriptional regulation, cellular differentiation and proliferation, DNA damage repair, viral suppression, and apoptosis. Its functionality is dependent upon post-translational modifications. Phosphorylation of KAP1 acts as a deactivator of the protein in many of its mechanisms while sumoylation acts as an activator.

    Synonyms: E3 SUMO protein ligase TRIM28 antibody|E3 SUMO-protein ligase TRIM28 antibody|FLJ29029 antibody|KAP 1 antibody|KAP-1 antibody|KRAB associated protein 1 antibody|KRAB interacting protein 1 antibody|KRAB-associated protein 1 antibody|KRAB-interacting protein 1 antibody|KRIP 1 antibody|KRIP-1 antibody|KRIP1 antibody|Nuclear corepressor KAP 1 antibody|Nuclear corepressor KAP-1 antibody|RING finger protein 96 antibody|RNF96 antibody|TF1B antibody|TIF1 beta antibody|TIF1-beta antibody|TIF1B antibody|TIF1B_HUMAN antibody| Transcription intermediary factor 1 beta antibody|Transcription intermediary factor 1-beta antibody|Trim28 antibody|Tripartite motif containing 28 antibody|tripartite motif containing protein 28 antibody|Tripartite motif-containing protein 28 antibody
    基因ID
    10155
    UniProt
    Q13263
    途径
    Hedgehog Signaling, Positive Regulation of Response to DNA Damage Stimulus
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