BAK1 抗体
Our Local Distributor
北京 101111
Quick Overview for BAK1 抗体 (ABIN645850)
抗原
See all BAK1 抗体适用
宿主
标记
应用范围
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特异性
- The goat Anti-BAK1 antibody detects protein derived from human recombinant protein and A431 cell lysate at various concentrations.
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交叉反应
- 小鼠, 大鼠
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产品特性
- Goat Anti-BAK1
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免疫原
- Peptide with sequence C-ASGQGPGPPRQE, from the N Terminus of the protein sequence according to NP_001179, was used as immunogen.
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亚型
- IgG
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限制
- 仅限研究用
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溶解方式
- Supplied as 100µg of purified antibody. 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Please avoid freeze-thaw cycles.
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储存条件
- -20 °C
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- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
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别名
- BAK1
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背景
- The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
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NCBI登录号
- NP_001179
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途径
- Apoptosis, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
抗原
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