MDM2 抗体
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北京 101111
Quick Overview for MDM2 抗体 (ABIN643838)
抗原
See all MDM2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse Anti-Human MDM2
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特异性
- DS-MB-01877 recognizes the 90kD MDM2 protein, which forms a complex with p53 leading to p53 inhibition. DS-MB-01877 also acts to stimulate cell proliferation via its induction of transcription factors such as E2F1 and DPI. It is over expressed in a range of human malignancies, including soft tissue sarcomas, breast cancer and bladder cancer. reacts with: Mouse. Antibody reactivity and working conditions may vary between species.
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产品特性
- Transcription and its regulation
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纯化方法
- Purified
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免疫原
- Synthetic peptide, CSRPSTSSRRRAISE, corresponding to amino acids 154-167 of human MDM2.
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亚型
- IgG1
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应用备注
- Immunohistology - Frozen, Immunoprecipitation, Immunohistology - Paraffin, Immunohistology - Resin
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限制
- 仅限研究用
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浓度
- IgG concentration 1.0 mg/ml
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缓冲液
- Phosphate buffered saline pH7.4
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C
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- MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
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别名
- MDM2
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途径
- p53 Pathway, PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Autophagy, Ubiquitin Proteasome Pathway
抗原
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