HLA-ABC 抗体
Quick Overview for HLA-ABC 抗体 (ABIN642915)
抗原
See all HLA-ABC 抗体适用
宿主
标记
应用范围
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特异性
- The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. There are 3 major MHC class I proteins encoded by the HLA which are HLA A, HLA B and HLA C. These proteins are found on the surface of almost all nucleated somatic cells. DS-MB-01537 recognizes a monomorphic determinant on the human HLA Class I heavy chain. Epitope analysis has shown that this antibody binds in the alpha1 domain. Recent studies have shown that this antibody may be able to induce apoptosis in activated but not resting T cells (1).
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产品特性
- Rat Anti-Human HLA ABC
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纯化方法
- Purified
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免疫原
- PhA activated human peripheral blood lymphocytes.
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亚型
- IgG2b
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限制
- 仅限研究用
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浓度
- IgG concentration 1.0 mg/ml
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缓冲液
- Phosphate buffered saline
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- HLA-ABC
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别名
- HLA ABC
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背景
- This antibody does not cross reacts with Fab or F(ab')2 of IgG. Some cross reaction with IgG of other species such as horse and sheep was observed. No cross reaction with human IgA, IgE or IgM.
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途径
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
抗原
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