Connexin 43/GJA1 抗体
Quick Overview for Connexin 43/GJA1 抗体 (ABIN641009)
抗原
See all Connexin 43/GJA1 (GJA1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-Chicken Connexin 43 (pSer368)
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特异性
- This product recognizes chicken Interferon gamma (chIFN-gamma). Original studies investigating the properties of chicken Interferon (chIFN), revealed properties similar to mammalian IFN type I (IFNI), and it has since become apparent that there are at least three distinct chicken interferon proteins, designated as chIFN-alpha, chIFN-beta and chIFN-gamma. chIFN-gamma was first identified, when supernatant from chicken spleen cells stimulated with concanavalin A (ConA ), displayed macrophage-activating factor (MAF) activity - the principle function of mammalian type II IFN-gamma. Several independent studies have since supported the existence of this chicken homolog, by the cloning of IFN-gamma cDNA from activated chicken T cells and demonstrating that recombinant chicken IFN-gamma strongly upregulates the expression of MHC class II and iNOS genes. It can be used to neutralize chIFN-gamma activity and to discriminate the antiviral activity of chIFN-gamma from that of chIFN-alpha and chIFN-beta (2).
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产品特性
- Adhesion Molecule/Cell Surface
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免疫原
- Antisera to chicken Interferon Gamma were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography on protein G.
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亚型
- IgG
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应用备注
- ELISA, Functional Assays, Western Blotting
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限制
- 仅限研究用
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浓度
- IgG concentration 0.5 mg/ml
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缓冲液
- Phosphate buffered saline
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- -20°C
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- Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
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别名
- Connexin 43
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途径
- MAPK Pathway, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization
抗原
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