IGF1 抗体 (Biotin)
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北京 101111
Quick Overview for IGF1 抗体 (Biotin) (ABIN640174)
抗原
See all IGF1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-Human IGF1 [+Biotin]
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特异性
- DS-PB-02646 is specific for human IGF-I (Insulin-like Growth Factor I), a 70 amino acid secreted mitogenic polypeptide and member of the insulin gene family, produced primarily by the liver. IGF-I exhibits both autocrine and paracrine properties and has a widespread effect on cells including those of the bone, cartilage, muscle, nerves, skin, liver and lungs, playing a key role in cell proliferation and growth, inhibition of apoptosis and linked with tumor cell growth. IGF-I signals through binding to the type 1 insulin-like growth factor receptor (IGF-1R) and also to the insulin receptor (IR), resulting in the activation of the AKT signaling pathway. Production of IGF-I is stimulated by growth hormone (GH) and can be hindered by GH insensitivity, deficiency in GH receptors or a malfunction in the post GH receptor signaling pathway.
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产品特性
- Cytokines/Chemokines/Growth Factors/Receptors
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免疫原
- Antisera to human IGF-I were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
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亚型
- IgG
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anti-Insulin-Like Growth Factor 1 (IGF1) (AA 49-118) antibody
IGF1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor 1 (IGF1) (AA 49-118) antibodyIGF1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C10 unconjugated
anti-Insulin-Like Growth Factor 1 (IGF1) (AA 49-118) antibodyIGF1 适用: 人 WB, ICC, IF 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Insulin-Like Growth Factor 1 (IGF1) (AA 49-153) antibodyIGF1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor 1 (IGF1) (Internal Region) antibodyVerified IGF1 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Insulin-Like Growth Factor 1 (IGF1) (AA 115-144), (C-Term) antibodyIGF1 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB33711 unconjugated
anti-Insulin-Like Growth Factor 1 (IGF1) (AA 115-144) antibodyIGF1 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor 1 (IGF1) (AA 49-100) antibodyIGF1 适用: 人, 小鼠, 大鼠, 犬 WB, IP, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor 1 (IGF1) (AA 33-102) antibodyIGF1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor 1 (IGF1) antibody (Atto 488)IGF1 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal Atto 488
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应用备注
- ELISA (dilution: 0.1, 0.2 μg/mL), Western Blotting
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限制
- 仅限研究用
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溶解方式
- Reconstitute with 0.5 mL sterile PBS containing 0.1 % Bovine Serum Albumin.. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. RayBiotech recommend that the vial is gently mixed after reconstitution. For long term storage the addition of 0.09 % sodium azide is recommended.
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浓度
- IgG concentration 0.1 mg/ml
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缓冲液
- Phosphate buffered saline pH7.2
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储存条件
- -20 °C
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储存方法
- -20°C
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- IGF1 (Insulin-Like Growth Factor 1 (IGF1))
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别名
- Insulin-Like Growth Factor I
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途径
- RTK signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation
抗原
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