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OLR1 抗体 (Soluble)

OLR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN639899
发货至: 中国
  • 抗原 See all OLR1 抗体
    OLR1 (Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1))
    抗原表位
    • 16
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
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    • 1
    Soluble
    适用
    • 58
    • 25
    • 22
    • 18
    • 2
    宿主
    • 40
    • 21
    • 2
    • 2
    • 1
    • 1
    小鼠
    克隆类型
    • 45
    • 22
    单克隆
    标记
    • 36
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This OLR1 antibody is un-conjugated
    应用范围
    • 46
    • 27
    • 21
    • 13
    • 13
    • 13
    • 11
    • 9
    • 8
    • 7
    • 6
    • 4
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    Western Blotting (WB), ELISA
    原理
    Mouse Anti-Human LOX-1 (soluble)
    特异性
    DS-MB-03380 recognizes the lectin-like oxidised low-density lipoprotein (LDL) receptor (LOX-1), a 31kDa protein of the C-type lectin superfamily. This receptor mediates the recognition, internalization and degradation of oxidized LDL. It is a Type II membrane protein with a typical C-type lectin structure at the extracellular C-terminus which recognizes the ligand. LOX-1 activation by oxidized LDL causes endothelial changes such as decreased nitric oxide release and an increased expression of adhesion molecules. LOX-1 also binds activated platelets and apoptotic cells. The expression of LOX-1 is induced by proatherogenic conditions such as hyperlipidemia, hypertension and diabetes and as such appears to contribute to the pathogenesis of vascular disorders, particularly atherosclerosis. It can be cleaved by an unknown protease at the extracellular juxtamembrane region to release the soluble form (aa58-273) of LOX-1, recognized by DS-MB-03380
    纯化方法
    Purified
    免疫原
    Recombinant soluble LOX-1 expressed in E.coli.
    亚型
    IgG1
    Top Product
    Discover our top product OLR1 Primary Antibody
  • 应用备注
    ELISA, Western Blotting
    限制
    仅限研究用
  • 浓度
    IgG concentration 1.0 mg/ml
    缓冲液
    Phosphate buffered saline pH7.4
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C
  • 抗原
    OLR1 (Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1))
    别名
    LOX-1 (OLR1 产品)
    别名
    OLR1 antibody, LOX1 antibody, Olr1 antibody, CLEC8A antibody, LOXIN antibody, SCARE1 antibody, SLOX1 antibody, LOX-1 antibody, SR-EI antibody, Scare1 antibody, Oldlr1 antibody, Oldr1 antibody, PLOX-1 antibody, oxidized low density lipoprotein receptor 1 antibody, oxidized low density lipoprotein (lectin-like) receptor 1 antibody, OLR1 antibody, Olr1 antibody
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