TNF alpha 抗体
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北京 101111
Quick Overview for TNF alpha 抗体 (ABIN639404)
抗原
See all TNF alpha 抗体适用
宿主
标记
应用范围
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特异性
- DS-MB-02427 is specific for mouse tumor necrosis factor alpha (TNF alpha), a 17 KDa cytokine produced by monocytes, macrophages, neutrophils, NK cells and CD4+ T cells. TNF alpha forms dimers and trimers, and is also found as a 26KDa integral membrane protein. Mouse TNF alpha has cytolytic activity against many tumor cell lines, and has an important immuno-regulatory role. DS-MB-02427 is reported to neutralize the effects of mouse TNF alpha (4,5).
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交叉反应
- 大鼠
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产品特性
- Rat Anti-Mouse Tumor Necrosis Factor alpha (TNF-alpha)
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纯化方法
- Purified
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免疫原
- Recombinant murine TNF alpha expressed in E. coli
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亚型
- IgG1
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限制
- 仅限研究用
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浓度
- IgG concentration 1.0 mg/ml
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缓冲液
- Phosphate buffered saline
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
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别名
- Tumor Necrosis Factor alpha (TNF-alpha)
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途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
抗原
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