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beta-2 Microglobulin 抗体

B2M 适用: 人 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN636142
发货至: 中国
  • 抗原 See all beta-2 Microglobulin (B2M) 抗体
    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
    适用
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    山羊
    克隆类型
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    多克隆
    标记
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    This beta-2 Microglobulin antibody is un-conjugated
    应用范围
    请咨询
    特异性
    Beta 2 Microglobulin antibody was raised against Human Beta-2-Microglobulin.
    纯化方法
    Affinity purified
    纯度
    > 95 % pure
    过滤
    Filtered
    免疫原
    Human beta-2-microglobulin
    Goat serum was obtained from healthy animals of US origin and under the care of a registered veterinarian.
    Top Product
    Discover our top product B2M Primary Antibody
  • 应用备注
    Optimal conditions should be determined byt he investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Clear, colorless liquid, 0.2 µm filtered, containing 10 mM Sodium Phosphate, 0.15 M Sodium Chloride and 0.05 % (w/v) Sodium Azide. Protease/IgG free.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8 °C.
  • 抗原
    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
    别名
    beta 2 Microglobulin (B2M 产品)
    别名
    Ly-m11 antibody, beta2-m antibody, beta2m antibody, bwm antibody, wu:fa94c05 antibody, wu:fb10a09 antibody, b2m-W01 antibody, b2m-W03 antibody, b2m-Z01 antibody, b2m-Z02 antibody, b2m-Z03 antibody, B2M antibody, b2m antibody, B2MG antibody, wu:fb66f11 antibody, wu:fj01f08 antibody, zgc:64161 antibody, b-2-m antibody, beta-2-microglobulin antibody, beta-2 microglobulin antibody, beta-2-microglobulin S homeolog antibody, beta-2-microglobulin, like antibody, B2M antibody, B2m antibody, b2m antibody, b2m.S antibody, b2ml antibody
    背景
    Beta 2 Microglobulin is a low molecular weight protein with sequence homology to immunoglobulins. As a portion of the HLA complex this protein is an important cell-surface structure. Under normal conditions Beta 2 Microglobulin is synthesized and shed by many cells, particularly lymphocytes, and is detectable in the circulation of normal individuals. Because of its small size it is normally filtered readily at the glomerulus and is catabolized by proximal tubular cells of the kidney. Impaired renal function and hyperproduction of Beta 2 Microglobulin are both associated with increased serum levels. A function for Beta 2 Microglobulin as a modulator of lymphocyte surface and as a potential regulator of the immune system is proposed.
    途径
    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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