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INSIG1 抗体 (Middle Region)

This anti-INSIG1 antibody is a 兔 多克隆 antibody detecting INSIG1 in WB. Suitable for 人.
产品编号 ABIN635185
发货至: 中国

Quick Overview for INSIG1 抗体 (Middle Region) (ABIN635185)

抗原

See all INSIG1 抗体
INSIG1 (Insulin Induced Gene 1 (INSIG1))

适用

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宿主

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克隆类型

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多克隆

标记

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This INSIG1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    特异性

    INSIG1 antibody was raised against the middle region of INSIG1

    纯化方法

    Affinity purified

    免疫原

    INSIG1 antibody was raised using the middle region of INSIG1 corresponding to a region with amino acids TTWLFHKTRSNYRVFLKSPIVIESSKPPILRARKILEENLTVDYDKDYLF
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    INSIG1 Blocking Peptide, catalog no. 33R-9337, is also available for use as a blocking control in assays to test for specificity of this INSIG1 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of INSIG1 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    INSIG1 (Insulin Induced Gene 1 (INSIG1))

    别名

    INSIG1

    背景

    Oxysterols regulate cholesterol homeostasis through the liver X receptor (LXR)- and sterol regulatory element-binding protein (SREBP)-mediated signaling pathways. This gene is an insulin-induced gene. INSIG1 is an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. INSIG1 binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins.

    分子量

    36 kDa (MW of target protein)

    途径

    ER-Nucleus Signaling
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