FBXW7 抗体 (C-Term)
Quick Overview for FBXW7 抗体 (C-Term) (ABIN635114)
抗原
See all FBXW7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- FBXW7 antibody was raised against the C terminal of FBXW7
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纯化方法
- Affinity purified
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免疫原
- FBXW7 antibody was raised using the C terminal of FBXW7 corresponding to a region with amino acids LKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVL
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应用备注
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WB: 0.25 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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FBXW7 Blocking Peptide, (ABIN940494), is also available for use as a blocking control in assays to test for specificity of this FBXW7 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of FBXW7 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
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别名
- FBXW7
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背景
- FBXW7 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs.
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分子量
- 66 kDa (MW of target protein)
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途径
- Notch Signaling, EGFR Signaling Pathway
抗原
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