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KCNQ2 抗体 (N-Term)

KCNQ2 适用: 大鼠, 人, 小鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN633754
发货至: 中国
  • 抗原 See all KCNQ2 抗体
    KCNQ2 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2))
    抗原表位
    • 16
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 31
    • 20
    • 15
    • 12
    • 11
    • 7
    • 7
    • 5
    • 5
    • 5
    • 2
    • 2
    大鼠, 人, 小鼠, 犬
    宿主
    • 35
    • 1
    克隆类型
    • 36
    多克隆
    标记
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KCNQ2 antibody is un-conjugated
    应用范围
    • 18
    • 16
    • 13
    • 13
    • 8
    • 8
    • 7
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB)
    特异性
    KCNQ2 antibody was raised against the N terminal of KCNQ2
    纯化方法
    Affinity purified
    免疫原
    KCNQ2 antibody was raised using the N terminal of KCNQ2 corresponding to a region with amino acids YRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFL
    Top Product
    Discover our top product KCNQ2 Primary Antibody
  • 应用备注
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    说明

    KCNQ2 Blocking Peptide, catalog no. 33R-10224, is also available for use as a blocking control in assays to test for specificity of this KCNQ2 antibody

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of KCNQ2 antibody in PBS
    浓度
    Lot specific
    缓冲液
    PBS
    注意事项
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原
    KCNQ2 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2))
    别名
    KCNQ2 (KCNQ2 产品)
    别名
    BFNC antibody, BFNS1 antibody, EBN antibody, EBN1 antibody, EIEE7 antibody, ENB1 antibody, HNSPC antibody, KCNA11 antibody, KV7.2 antibody, KVEBN1 antibody, KQT2 antibody, Nmf134 antibody, mKQT2.3 antibody, mKQT2.4 antibody, zgc:171872 antibody, potassium voltage-gated channel subfamily Q member 2 antibody, potassium voltage-gated channel, subfamily Q, member 2 antibody, potassium voltage-gated channel subfamily KQT member 2 antibody, potassium voltage-gated channel, KQT-like subfamily, member 2a antibody, KCNQ2 antibody, Kcnq2 antibody, LOC100537363 antibody, kcnq2a antibody
    背景
    The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by KCNQ2 and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in KCNQ2 are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1).
    分子量
    93 kDa (MW of target protein)
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