MGMT 抗体 (Middle Region)
Quick Overview for MGMT 抗体 (Middle Region) (ABIN631949)
抗原
See all MGMT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- MGMT antibody was raised against the middle region of MGMT
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纯化方法
- Affinity purified
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免疫原
- MGMT antibody was raised using the middle region of MGMT corresponding to a region with amino acids ISYQQLAALAGNPKAARAVGGAMRGNPVPILIPCHRVVCSSGAVGNYSGG
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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MGMT Blocking Peptide, (ABIN939556), is also available for use as a blocking control in assays to test for specificity of this MGMT antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of MGMT antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
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别名
- MGMT
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背景
- MGMT is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA.MGMT repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
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分子量
- 22 kDa (MW of target protein)
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途径
- DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
抗原
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