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MCM2 抗体 (N-Term)

The 兔 多克隆 anti-MCM2 antibody (ABIN630186) specifically detects MCM2 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN630186
发货至: 中国
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Quick Overview for MCM2 抗体 (N-Term) (ABIN630186)

抗原

See all MCM2 抗体
MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

适用

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克隆类型

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多克隆

标记

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This MCM2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
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    N-Term

    特异性

    MCM2 antibody was raised against the N terminal of MCM2

    纯化方法

    Purified

    免疫原

    MCM2 antibody was raised using the N terminal of MCM2 corresponding to a region with amino acids PGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEGPLEEEEDGEELIGDGM
  • 应用备注

    WB: 1.25 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    MCM2 Blocking Peptide, (ABIN5614697), is also available for use as a blocking control in assays to test for specificity of this MCM2 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of MCM2 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

    别名

    MCM2

    背景

    The protein encoded by MCM2 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.

    分子量

    99 kDa (MW of target protein)

    途径

    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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