MCM2 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for MCM2 抗体 (N-Term) (ABIN630186)
抗原
See all MCM2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
特异性
- MCM2 antibody was raised against the N terminal of MCM2
-
纯化方法
- Purified
-
免疫原
- MCM2 antibody was raised using the N terminal of MCM2 corresponding to a region with amino acids PGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEGPLEEEEDGEELIGDGM
-
-
-
-
应用备注
-
WB: 1.25 µg/mL
Optimal conditions should be determined by the investigator. -
说明
-
MCM2 Blocking Peptide, (ABIN5614697), is also available for use as a blocking control in assays to test for specificity of this MCM2 antibody
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of MCM2 antibody in PBS
-
浓度
- Lot specific
-
缓冲液
- PBS
-
注意事项
-
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
-
-
- MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))
-
别名
- MCM2
-
背景
- The protein encoded by MCM2 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.
-
分子量
- 99 kDa (MW of target protein)
-
途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
抗原
-