KCNQ2 抗体 (Middle Region)
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- 抗原 See all KCNQ2 抗体
- KCNQ2 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2))
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抗原表位
- Middle Region
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适用
- 大鼠, 人, 小鼠, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KCNQ2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- KCNQ2 antibody was raised against the middle region of KCNQ2
- 纯化方法
- Purified
- 免疫原
- KCNQ2 antibody was raised using the middle region of KCNQ2 corresponding to a region with amino acids GNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYI
- Top Product
- Discover our top product KCNQ2 Primary Antibody
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- 应用备注
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WB: 1.25 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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KCNQ2 Blocking Peptide, catalog no. 33R-3461, is also available for use as a blocking control in assays to test for specificity of this KCNQ2 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of KCNQ2 antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- KCNQ2 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2))
- 别名
- KCNQ2 (KCNQ2 产品)
- 别名
- BFNC antibody, BFNS1 antibody, EBN antibody, EBN1 antibody, EIEE7 antibody, ENB1 antibody, HNSPC antibody, KCNA11 antibody, KV7.2 antibody, KVEBN1 antibody, KQT2 antibody, Nmf134 antibody, mKQT2.3 antibody, mKQT2.4 antibody, zgc:171872 antibody, potassium voltage-gated channel subfamily Q member 2 antibody, potassium voltage-gated channel, subfamily Q, member 2 antibody, potassium voltage-gated channel subfamily KQT member 2 antibody, potassium voltage-gated channel, KQT-like subfamily, member 2a antibody, KCNQ2 antibody, Kcnq2 antibody, LOC100537363 antibody, kcnq2a antibody
- 背景
- The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by the KCNQ2 gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in KCNQ2 are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1).
- 分子量
- 43 kDa (MW of target protein)
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