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EGFR 抗体

EGFR 适用: 人 IF, FACS, IHC (fp) 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN6297747
发货至: 中国
  • 抗原 See all EGFR 抗体
    EGFR (Epidermal Growth Factor Receptor (EGFR))
    适用
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    小鼠
    克隆类型
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    单克隆
    标记
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    This EGFR antibody is un-conjugated
    应用范围
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    Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
    原理
    Mouse anti-Human EGFR Antibody [Sodium Azide Free]
    特异性
    Cell surface
    纯化方法
    The immunizing protein for this antibody was recombinant human EGFR.
    免疫原
    The immunizing protein for this antibody was recombinant human EGFR.
    Top Product
    Discover our top product EGFR Primary Antibody
  • 应用备注
    IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
    FACS: 0.5-1 μg/million cells in 0.1ml
    IF: 1-2 μg/mL
    限制
    仅限研究用
  • 缓冲液
    In 1X PBS ( pH 7.4), BSA free, sodium azide free
    储存液
    Azide free
    储存条件
    4 °C,-20 °C
    储存方法
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原
    EGFR (Epidermal Growth Factor Receptor (EGFR))
    别名
    Epidermal growth factor receptor (EGFR 产品)
    背景

    Target Description: This antibody recognizes a protein of 170 kDa, identified as EGFR.  < a href=../search_result.php?search_txt=egfr>EGFR  is type I receptor tyrosine kinase with sequence homology to  < a href=../search_result.php?search_txt=erbb2>ErbB2, -3 -4 or  < a href=../search_result.php?search_txt=her2>HER2, -3 -4. It binds to Epidermal Growth Factor (EGF),  < a href=../search_result.php?search_txt=TGFa>Transforming Growth Factor-a  (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head/neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

    Gene Symbol: EGFR///ERBB///ERBB1///HER1

    基因ID
    1956
    UniProt
    P00533
    途径
    NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
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