CD44 抗体
Quick Overview for CD44 抗体 (ABIN6297699)
抗原
See all CD44 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human/Baboon/Green Monkey HCAM Antibody CD44 [Sodium Azide Free]
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特异性
- Cell surface
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纯化方法
- Stimulated human leukocytes were used as the immunogen for this CD44 / HCAM antibody.
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免疫原
- Stimulated human leukocytes were used as the immunogen for this CD44 / HCAM antibody.
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应用备注
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ELISA: order BSA-free format for coating
FACS: 0.5-1 μg/million cells
IF: 0.5-1 μg/mL
WB: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2) -
限制
- 仅限研究用
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缓冲液
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- CD44
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别名
- CD44 antigen
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背景
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Target Description: This antibody recognizes a cell surface glycoprotein of 80-95 kDa, called CD44, or HCAM, on lymphocytes, monocytes, and granulocytes (Leucocyte Typing Workshop V). Its epitope is resistant to digestion by trypsin and chymotrypsin. The CD44 family of glycoproteins exists in a number of variant isoforms, the most common being the standard 85-95 kDa or hematopoietic variant (CD44-s). Higher molecular weight isoforms are described in epithelial cells (CD44-v), which are believed to function in intercellular adhesion and stromal binding. HCAM antibody immunostaining is commonly used for the discrimination of urothelial transitional cell carcinoma in-situ from non-neoplastic changes in the urothelium.
Gene Symbol: CD44///LHR///MDU2///MDU3///MIC4
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基因ID
- 960
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UniProt
- P16070
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途径
- Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
抗原
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