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- 抗原 See all PARP1 抗体
- PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
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适用
- 人, 小鼠, 大鼠, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PARP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Purified
- 免疫原
- PARP1 antibody was raised using a synthetic peptide corresponding to a region with amino acids ISRLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVIDTSLLYN
- Top Product
- Discover our top product PARP1 Primary Antibody
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anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 81-390) antibody
PARP1 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) antibodyKO Validated PARP1 适用: 人 WB, IP, IF, ICC, IHC (p), ChIP 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 201-300) antibodyPARP1 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 661-881) antibodyPARP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 140-220), (Cleaved-Asp214) antibodyPARP1 适用: 人, 小鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (C-Term) antibodyPARP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 1-100) antibodyPARP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3G4 unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 670-858) antibodyPARP1 适用: 人, 小鼠, 大鼠 WB, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (cleaved) antibodyPARP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) antibodyPARP1 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 兔 Monoclonal 8C7 unconjugated Recombinant Antibody
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- 应用备注
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WB: 5 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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PARP1 Blocking Peptide, catalog no. 33R-4164, is also available for use as a blocking control in assays to test for specificity of this PARP1 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PARP1 antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
- 别名
- PARP1 (PARP1 产品)
- 别名
- ADPRT antibody, ADPRT 1 antibody, ADPRT1 antibody, ARTD1 antibody, PARP antibody, PARP-1 antibody, PPOL antibody, pADPRT-1 antibody, Adprt antibody, Parp-1 antibody, 5830444G22Rik antibody, AI893648 antibody, Adprp antibody, Adprt1 antibody, C80510 antibody, parp-1 antibody, sPARP-1 antibody, BEST:LD21673 antibody, CG17685 antibody, CG17696 antibody, CG17718 antibody, CG40411 antibody, D.PARP antibody, Dm.pARTa antibody, Dmel\\CG40411 antibody, LD21673.3prime antibody, PARP1 antibody, dPARP antibody, parp antibody, adprt1 antibody, padprt-1 antibody, ppol antibody, si:dkey-206f10.3 antibody, wu:fc60f12 antibody, zgc:110092 antibody, poly(ADP-ribose) polymerase 1 antibody, poly (ADP-ribose) polymerase 1 antibody, poly (ADP-ribose) polymerase family, member 1 antibody, Poly-(ADP-ribose) polymerase antibody, poly(ADP-ribose) polymerase 1 L homeolog antibody, PARP1 antibody, Parp1 antibody, Parp antibody, parp1.L antibody, parp1 antibody
- 背景
- PARP1 encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. PARP1 can be cleaved resulting in fragements of 29 and 85 kDa.
- 分子量
- 113 kDa (MW of target protein)
- 途径
- Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
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