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RUNX2 抗体 (Middle Region)

This anti-RUNX2 antibody is a 兔 多克隆 antibody detecting RUNX2 in WB. Suitable for 人, 小鼠, 大鼠 和 犬.
产品编号 ABIN629583
发货至: 中国

Quick Overview for RUNX2 抗体 (Middle Region) (ABIN629583)

抗原

See all RUNX2 抗体
RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

适用

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人, 小鼠, 大鼠, 犬

宿主

  • 122
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克隆类型

  • 113
  • 25
多克隆

标记

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This RUNX2 antibody is un-conjugated

应用范围

  • 106
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Western Blotting (WB)
  • 抗原表位

    • 16
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    Middle Region

    特异性

    RUNX2 antibody was raised against the middle region of RUNX2

    纯化方法

    Purified

    免疫原

    RUNX2 antibody was raised using the middle region of RUNX2 corresponding to a region with amino acids DTATSDFCLWPSTLSKKSQAGASELGPFSDPRQFPSISSLTESRFSNPRM
  • 应用备注

    WB: 1.25 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    RUNX2 Blocking Peptide, (ABIN937574), is also available for use as a blocking control in assays to test for specificity of this RUNX2 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of RUNX2 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

    别名

    RUNX2

    背景

    RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis, acting as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants, encoding different protein isoforms, result from alternate promoter use as well as alternate splicing.

    分子量

    57 kDa (MW of target protein)
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