PES1 抗体
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- 抗原 See all PES1 抗体
- PES1 (Pescadillo Ribosomal Biogenesis Factor 1 (PES1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PES1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human PES1
- 亚型
- IgG
- Top Product
- Discover our top product PES1 Primary Antibody
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- 应用备注
- WB 1:500 - 1:2000
- 说明
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Significant levels are detected in a variety of cancer cell lines, including glioblastoma, breast carcinoma, colon carcinoma and cervical carcinoma cells, Levels are abnormally elevated in malignant tumors of astrocytic origin
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20C. Avoid freeze / thaw cycles.
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- 抗原
- PES1 (Pescadillo Ribosomal Biogenesis Factor 1 (PES1))
- 别名
- PES1 (PES1 产品)
- 别名
- PES antibody, pes antibody, pes1 antibody, pescadillo ribosomal biogenesis factor 1 antibody, pescadillo ribosomal biogenesis factor 1 S homeolog antibody, Pescadillo antibody, PES1 antibody, Pes1 antibody, pes1.S antibody, pesc antibody
- 背景
- This gene encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. The encoded protein interacts with BOP1 and WDR12 to form the PeBoW complex, which plays a critical role in cell proliferation via pre-rRNA processing and 60S ribosomal subunit maturation. Expression of this gene may play an important role in breast cancer proliferation and tumorigenicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the long arm of chromosome 4 and the short arm of chromosome 9.
- 分子量
- 68.003 kDa
- 基因ID
- 23481
- UniProt
- O00541
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