RASGRP2 抗体
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- 抗原 See all RASGRP2 抗体
- RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RASGRP2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human RASGRP2
- 亚型
- IgG
- Top Product
- Discover our top product RASGRP2 Primary Antibody
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- 应用备注
- WB 1:200 - 1:2000
- 说明
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Detected in platelets, neutrophils and T lymphocytes (at protein level), Expressed in brain where it is enriched in the striatum, Also expressed in the hematopoietic system, Detected in heart, brain, lung, placenta, liver, skeletal muscle and kidney
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20C. Avoid freeze / thaw cycles.
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- 抗原
- RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))
- 别名
- RASGRP2 (RASGRP2 产品)
- 别名
- CALDAG-GEFI antibody, CDC25L antibody, xrasgrp2 antibody, RASGRP2 antibody, Caldaggef1 antibody, CalDAG-GEFI antibody, rasgrp2 antibody, RAS guanyl releasing protein 2 antibody, RAS guanyl releasing protein 2 (calcium and DAG-regulated) S homeolog antibody, RAS, guanyl releasing protein 2 antibody, RAS guanyl releasing protein 2 (calcium and DAG-regulated) L homeolog antibody, RASGRP2 antibody, rasgrp2.S antibody, Rasgrp2 antibody, rasgrp2.L antibody
- 背景
- The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene.
- 分子量
- 69.248 kDa
- 基因ID
- 10235
- UniProt
- Q7LDG7
- 途径
- TCR Signaling
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