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ITGB3BP 抗体

ITGB3BP 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6293028
发货至: 中国
  • 抗原 See all ITGB3BP 抗体
    ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))
    适用
    • 23
    • 4
    • 3
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 21
    • 2
    克隆类型
    • 21
    • 2
    多克隆
    标记
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ITGB3BP antibody is un-conjugated
    应用范围
    • 12
    • 8
    • 7
    • 2
    Immunohistochemistry (IHC)
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human ITGB3BP
    亚型
    IgG
    Top Product
    Discover our top product ITGB3BP Primary Antibody
  • 应用备注
    IHC 1:50 - 1:200
    说明

    Widely expressed, Expressed in spleen, thymus, prostate, ovary, small intestine and white blood cells, Highly expressed in testis and colon, Isoform 4 is expressed in platelets, lymphocytes and granulocytes

    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20C. Avoid freeze / thaw cycles.
  • 抗原
    ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))
    别名
    ITGB3BP (ITGB3BP 产品)
    别名
    CENP-R antibody, CENPR antibody, HSU37139 antibody, NRIF3 antibody, TAP20 antibody, 4930471O16Rik antibody, AU022583 antibody, integrin subunit beta 3 binding protein antibody, integrin beta 3 binding protein (beta3-endonexin) antibody, ITGB3BP antibody, Itgb3bp antibody
    背景
    This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.
    分子量
    20.194 kDa
    基因ID
    23421
    UniProt
    Q13352
    途径
    Neurotrophin Signaling Pathway
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