TCIRG1 抗体
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- 抗原 See all TCIRG1 抗体
- TCIRG1 (T-Cell, Immune Regulator 1, ATPase, H+ Transporting, Lysosomal V0 Subunit A3 (TCIRG1))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TCIRG1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human TCIRG1
- 亚型
- IgG
- Top Product
- Discover our top product TCIRG1 Primary Antibody
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- 应用备注
- WB 1:200 - 1:2000
- 说明
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Isoform long is highly expressed in osteoclastomas, Isoform short is highly expressed in thymus
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20C. Avoid freeze / thaw cycles.
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- 抗原
- TCIRG1 (T-Cell, Immune Regulator 1, ATPase, H+ Transporting, Lysosomal V0 Subunit A3 (TCIRG1))
- 别名
- TCIRG1 (TCIRG1 产品)
- 别名
- OC116 antibody, TIRC7 antibody, ATP6N1C antibody, ATP6a3 antibody, Atp6i antibody, OC-116 antibody, OPTB1 antibody, Stv1 antibody, Vph1 antibody, oc antibody, ATP6V0A3 antibody, OC-116kDa antibody, a3 antibody, T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 antibody, T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 antibody, T-cell immune regulator 1, ATPase H+ transporting V0 subunit a3 antibody, Tcirg1 antibody, TCIRG1 antibody
- 背景
- This gene encodes a subunit of a large protein complex known as a vacuolar H+-ATPase (V-ATPase). The protein complex acts as a pump to move protons across the membrane. This movement of protons helps regulate the pH of cells and their surrounding environment. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Alternative splicing results in multiple transcript variants. Mutations in this gene are associated with infantile malignant osteopetrosis.
- 分子量
- 92.968 kDa
- 基因ID
- 10312
- UniProt
- Q13488
- 途径
- Transition Metal Ion Homeostasis, Proton Transport
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