Reticulon 3 抗体
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- 抗原 See all Reticulon 3 (RTN3) 抗体
- Reticulon 3 (RTN3)
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Reticulon 3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity purification
- 免疫原
- A synthetic peptide of human RTN3
- 亚型
- IgG
- Top Product
- Discover our top product RTN3 Primary Antibody
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- 应用备注
- WB 1:500 - 1:2000
- 说明
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Isoform 3 is widely expressed, with highest levels in brain, where it is enriched in neuronal cell bodies from gray matter (at protein level), Three times more abundant in macula than in peripheral retina, Isoform 1 is expressed at high levels in brain and at low levels in skeletal muscle, Isoform 2 is only found in melanoma
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20C. Avoid freeze / thaw cycles.
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- 抗原
- Reticulon 3 (RTN3)
- 别名
- RTN3 (RTN3 产品)
- 别名
- ASYIP antibody, HAP antibody, NSPL2 antibody, NSPLII antibody, RTN3-A1 antibody, MGC56439 antibody, zgc:56439 antibody, zgc:77630 antibody, RTN3 antibody, hap antibody, asyip antibody, nspl2 antibody, xrtn3 antibody, nsplii antibody, rtn3-a1 antibody, RTN3w antibody, rtn3 antibody, XRTN3 antibody, rtn3-a antibody, rtn3-b antibody, reticulon 3 antibody, reticulon 3 L homeolog antibody, reticulon-3 antibody, reticulon 3 S homeolog antibody, RTN3 antibody, Rtn3 antibody, rtn3 antibody, rnt3 antibody, rtn3.L antibody, LOC107131155 antibody, rtn3.S antibody
- 背景
- This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12.
- 分子量
- 112.611 kDa
- 基因ID
- 10313
- UniProt
- O95197
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