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DUSP12 抗体

DUSP12 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6290306
发货至: 中国
  • 抗原 See all DUSP12 抗体
    DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))
    适用
    • 35
    • 12
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 32
    • 3
    克隆类型
    • 35
    多克隆
    标记
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DUSP12 antibody is un-conjugated
    应用范围
    • 27
    • 16
    • 2
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    Affinity purification
    免疫原
    Recombinant Protein of human DUSP12
    亚型
    IgG
    Top Product
    Discover our top product DUSP12 Primary Antibody
  • 应用备注
    WB 1:500 - 1:2000
    说明

    Ubiquitous, highest expression in spleen, testis, ovary, and peripheral blood leukocytes and lower expression in liver and lung

    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20C. Avoid freeze / thaw cycles.
  • 抗原
    DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))
    别名
    DUSP12 (DUSP12 产品)
    别名
    DUSP12 antibody, dusp12 antibody, zgc:114069 antibody, MGC154526 antibody, DUSP1 antibody, YVH1 antibody, 1190004O14Rik antibody, AA027408 antibody, AW049275 antibody, ESTM36 antibody, LMW-DSP4 antibody, T-DSP4 antibody, VH1 antibody, mVH1 antibody, GKAP antibody, dual specificity phosphatase 12 antibody, dual specificity phosphatase 12 L homeolog antibody, Dual specificity protein phosphatase 12 antibody, dual specificity protein phosphatase 12 antibody, DUSP12 antibody, dusp12 antibody, dusp12.L antibody, GL50803_36315 antibody, MGYG_01770 antibody, Dusp12 antibody
    背景
    The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.
    分子量
    37.687 kDa
    基因ID
    11266
    UniProt
    Q9UNI6
    途径
    Regulation of Carbohydrate Metabolic Process
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