GDF5 抗体
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- 抗原 See all GDF5 抗体
- GDF5 (Growth Differentiation Factor 5 (GDF5))
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GDF5 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity purification
- 免疫原
- A synthetic peptide of human GDF5
- 亚型
- IgG
- Top Product
- Discover our top product GDF5 Primary Antibody
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- 应用备注
- WB 1:500 - 1:2000
- 说明
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Predominantly expressed in long bones during embryonic development, Expressed in monocytes (at protein level)
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20C. Avoid freeze / thaw cycles.
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- 抗原
- GDF5 (Growth Differentiation Factor 5 (GDF5))
- 别名
- GDF5 (GDF5 产品)
- 别名
- CDMP1 antibody, gdf antibody, gdf-5 antibody, GDF5 antibody, BDA1C antibody, BMP14 antibody, LAP4 antibody, OS5 antibody, SYM1B antibody, SYNS2 antibody, Cdmp-1 antibody, bp antibody, brp antibody, Cdmp1 antibody, growth differentiation factor 5 L homeolog antibody, growth differentiation factor 5 antibody, gdf5.L antibody, GDF5 antibody, Gdf5 antibody
- 背景
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mutations in this gene are associated with acromesomelic dysplasia, brachydactyly, chondrodysplasia, multiple synostoses syndrome, proximal symphalangism, and susceptibility to osteoarthritis.
- 分子量
- 55.411 kDa
- 基因ID
- 8200
- UniProt
- P43026
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