GSK3 alpha/beta 抗体 (pTyr216, pTyr279)
-
- 抗原 See all GSK3 alpha/beta (GSK3a/b) products
- GSK3 alpha/beta (GSK3a/b) (Glycogen Synthase Kinase 3 alpha/beta (GSK3a/b))
-
抗原表位
- AA 220-300, pTyr216, pTyr279
-
适用
- 人, 大鼠, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This GSK3 alpha/beta antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- GSK3α/β is a protein encoded by the GSK3A gene which is approximately 50,9 kDa. GSK3α/β is localised to the mitochondrion. It is involved in the common cytokine receptor gamma-chain family signalling pathways, RET signalling and activation of cAMP-dependent PKA. It is a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also acts as a negative regulator in the hormonal control of glucose homeostasis. GSK3α/β is expressed in the nervous system, liver, eye, pancreas and muscle. Mutations in the GSK3A gene may result in Alzheimer disease. STJ90283 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody specifically binds to endogenous GSK3α/β protein which only binds about Y279/216 when Y279/216 is phosphorylated.
- 特异性
- Phospho-GSK3α/β (Y279/216) Polyclonal Antibody detects endogenous levels of GSK3α/β protein only when phosphorylated at Y279/216.
- 产品特性
- Rabbit polyclonal to Phospho-GSK3α/β (Y279/216).
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from human GSK3alpha/beta around the phosphorylation site of Y279/216.
- 亚型
- IgG
-
anti-Glycogen Synthase Kinase 3 alpha/beta (GSK3a/b) (pTyr216), (pTyr279) antibody
GSK3a/b 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (cc), FACS, IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase Kinase 3 alpha/beta (GSK3a/b) (Ser4520) antibodyGSK3a/b 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase Kinase 3 alpha/beta (GSK3a/b) antibodyGSK3a/b 适用: 人, 大鼠, 小鼠, 非洲爪蟾 WB, IHC, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal unconjugated
anti-Glycogen Synthase Kinase 3 alpha/beta (GSK3a/b) antibodyGSK3a/b 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase Kinase 3 alpha/beta (GSK3a/b) (Center) antibodyGSK3a/b 适用: 人, 大鼠, 小鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase Kinase 3 alpha/beta (GSK3a/b) (AA 246-295), (pTyr279) antibodyGSK3a/b 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase Kinase 3 alpha/beta (GSK3a/b) (pTyr216), (pTyr279) antibodyGSK3a/b 适用: 人, 大鼠, 小鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
-
- 抗原
- GSK3 alpha/beta (GSK3a/b) (Glycogen Synthase Kinase 3 alpha/beta (GSK3a/b))
- 别名
- GSK3alpha/beta (GSK3a/b 产品)
- 分子量
- 51 kDa
- 基因ID
- 2931
- UniProt
- P49840
-
