ADNP 抗体 (N-Term)
-
- 抗原 See all ADNP 抗体
- ADNP (Activity-Dependent Neuroprotector Homeobox (ADNP))
-
抗原表位
- AA 80-160, N-Term
-
适用
- 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This ADNP antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- ADNP is a protein encoded by the ADNP gene which is approximately 123,5 kDa. It is a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. It may also increase the viability of certain cell types through modulation of p53 activity. ADNP is widely expressed with strong expression in heart, skeletal muscle, kidney and placenta. Mutations in the ADNP gene may result in Helsmoortel-van der Aa syndrome. STJ91502 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of ADNP protein.
- 特异性
- ADNP Polyclonal Antibody detects endogenous levels of ADNP protein.
- 产品特性
- Rabbit polyclonal to ADNP.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from human ADNP
- 亚型
- IgG
- Top Product
- Discover our top product ADNP Primary Antibody
-
-
- 应用备注
-
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000 - 说明
-
Widely expressed. Strong expression in heart, skeletal muscle, kidney and placenta. In brain, expression is stronger in the cerebellum and cortex regions. No expression detected in the colon. Strong increase of expression in colon and breast cancer tissues.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
-
- 抗原
- ADNP (Activity-Dependent Neuroprotector Homeobox (ADNP))
- 别名
- ADNP (ADNP 产品)
- 别名
- AA589558 antibody, mKIAA0784 antibody, ADNP1 antibody, activity-dependent neuroprotective protein antibody, activity dependent neuroprotector homeobox antibody, activity-dependent neuroprotector homeobox antibody, Adnp antibody, ADNP antibody
- 分子量
- 124 kDa
- 基因ID
- 23394
- UniProt
- Q9H2P0
- 途径
- Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process
-