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Versican 抗体 (N-Term)

Vcan 适用: 人 ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6287760
发货至: 中国
  • 抗原 See all Versican (Vcan) 抗体
    Versican (Vcan)
    抗原表位
    • 15
    • 12
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 510-590, N-Term
    适用
    • 42
    • 36
    • 20
    • 4
    • 1
    • 1
    宿主
    • 43
    • 21
    • 1
    • 1
    克隆类型
    • 38
    • 28
    多克隆
    标记
    • 29
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Versican antibody is un-conjugated
    应用范围
    • 33
    • 15
    • 15
    • 14
    • 13
    • 13
    • 13
    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Versican is a protein encoded by the VCAN gene which is approximately 372,8 kDa. Versican is secreted into the extracellular space. It is involved in the integrin pathway, ERK signalling, glycosaminoglycan metabolism and phospholipase-C pathway. This protein falls under the aggrecan/versican proteoglycan family. It is a large chondroitin sulfate proteoglycan and is a major component of the extracellular matrix. This protein is involved in cell adhesion, proliferation, migration and angiogenesis and plays a central role in tissue morphogenesis and maintenance. Versican is expressed in the cerebral white matter and plasma. Mutations in the VCAN gene may result in wagner vitreoretinopathy. STJ96239 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of versican protein.
    特异性
    Versican Polyclonal Antibody detects endogenous levels of Versican protein.
    产品特性
    Rabbit polyclonal to Versican.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    Synthesized peptide derived from human Versican
    亚型
    IgG
    Top Product
    Discover our top product Vcan Primary Antibody
  • 应用备注
    IHC 1:100-1:300
    ELISA 1:10000
    说明

    Cerebral white matter and plasma. Isoform V0 and isoform V1 are expressed in normal brain, gliomas, medulloblastomas, schwannomas, neurofibromas, and meningiomas. Isoform V2 is restricted to normal brain and gliomas. Isoform V3 is found in all these tissues except medulloblastomas.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • 抗原
    Versican (Vcan)
    别名
    Versican (Vcan 产品)
    别名
    br146 antibody, cspg2 antibody, cspg2a antibody, sb:cb63 antibody, versican antibody, CSPG2 antibody, Cspg2 antibody, wgn antibody, ervr antibody, pg-m antibody, wgn1 antibody, Xversican antibody, dcan antibody, cspg2b antibody, fb99b07 antibody, wu:fb99b07 antibody, ERVR antibody, GHAP antibody, PG-M antibody, WGN antibody, WGN1 antibody, 5430420N07Rik antibody, 9430051N09 antibody, DPEAAE antibody, NG2 antibody, PG-M(V0) antibody, PG-M(V1) antibody, hdf antibody, versican a antibody, versican antibody, versican b antibody, vcana antibody, VCAN antibody, Vcan antibody, vcan antibody, vcanb antibody
    分子量
    372.82 kDa
    基因ID
    1462
    UniProt
    P13611
    途径
    Glycosaminoglycan Metabolic Process
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