GLUT4 抗体 (N-Term)
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- 抗原 See all GLUT4 (SLC2A4) 抗体
- GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))
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抗原表位
- AA 21-70, N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GLUT4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 原理
- Glut4 is a protein encoded by the SLC2A4 gene which is approximately 54,7 kDa. Glut4 is localised to the cell membrane and cytoplasm. It is involved in the transport of glucose, other sugars, bile salts, organic acids and metal ions and AMP-activated protein kinase signalling. This protein falls under the solute carrier family 2 and functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, it is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Glut4 is expressed in the skeletal and cardiac muscles, brown and white fat. Mutations in the SLC2A4 gene may be involved in diabetes mellitus. STJ96888 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Glut4 protein.
- 特异性
- Glut4 Polyclonal Antibody detects endogenous levels of Glut4 protein.
- 产品特性
- Rabbit polyclonal to Glut4.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from human Glut4.
- 亚型
- IgG
- Top Product
- Discover our top product SLC2A4 Primary Antibody
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- 应用备注
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WB 1:500-1:2000
ELISA 1:20000 - 说明
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Skeletal and cardiac muscles, brown and white fat.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- 抗原
- GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))
- 别名
- Glut4 (SLC2A4 产品)
- 别名
- GLUT4 antibody, Glut-4 antibody, Glut4 antibody, glut4 antibody, slc2a4 antibody, SLC2A4 antibody, solute carrier family 2 member 4 antibody, solute carrier family 2 (facilitated glucose transporter), member 4 antibody, solute carrier family 2 (facilitated glucose transporter), member 4 L homeolog antibody, SLC2A4 antibody, Slc2a4 antibody, GLUT4 antibody, slc2a4.L antibody
- 基因ID
- 6517
- UniProt
- P14672
- 途径
- AMPK Signaling, Carbohydrate Homeostasis, Proton Transport, Brown Fat Cell Differentiation, Warburg Effect
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