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TLN1 抗体 (C-Term)

TLN1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6285636
发货至: 中国
  • 抗原 See all TLN1 抗体
    TLN1 (Talin 1 (TLN1))
    抗原表位
    • 15
    • 6
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 42
    • 37
    • 26
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 43
    • 15
    • 1
    • 1
    克隆类型
    • 45
    • 15
    多克隆
    标记
    • 32
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLN1 antibody is un-conjugated
    应用范围
    • 30
    • 22
    • 13
    • 13
    • 8
    • 8
    • 8
    • 6
    • 6
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    原理
    Talin-1 is a protein encoded by the TLN1 gene which is approximately 269,2 kDa. Talin-1 is localised to the cytoplasm and cell surface. It is involved in RET signalling, integrin alphaIIb beta3 signalling, response to elevated platelet cytosolic Ca2+ and focal adhesion. It plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It co-distributes with integrins in the cell surface membrane in order to assist in the attachment of lymphocytes to other cells and attachment of adherent cells to extracellular matrices. Talin-1 is expressed in the blood, nervous system, liver, intestine and skin. Mutations in the TLN1 gene result in ovarian serous carcinoma. STJ97271 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Talin-1 protein.
    特异性
    Talin-1 Polyclonal Antibody detects endogenous levels of Talin-1 protein.
    产品特性
    Rabbit polyclonal to Talin-1.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    Synthesized peptide derived from human Talin-1.
    亚型
    IgG
    Top Product
    Discover our top product TLN1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000
    IHC-P 1:100-1:300
    ELISA 1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • 抗原
    TLN1 (Talin 1 (TLN1))
    别名
    Talin-1 (TLN1 产品)
    别名
    ILWEQ antibody, TLN antibody, Tln antibody, sb:cb854 antibody, wu:fb05c02 antibody, TLN1 antibody, talin-1 antibody, tln antibody, talin 1 antibody, talin 1 L homeolog antibody, Talin 1 antibody, talin-1 antibody, TLN1 antibody, Tln1 antibody, tln1 antibody, tln1.L antibody, Bm1_56490 antibody, LOC100380665 antibody
    基因ID
    7094
    UniProt
    Q9Y490
    途径
    Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location
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