Vinculin 抗体 (AA 760-840)
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- 抗原 See all Vinculin (VCL) 抗体
- Vinculin (VCL)
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抗原表位
- AA 760-840
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Vinculin antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Vinculin is a protein encoded by the VCL gene which is approximately 123,7 kDa. Vinculin is localised to the cell membrane. It is involved in RET signalling, signalling by moderate kinase activity BRAF mutants and focal adhesion. It is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. It may also play important roles in cell morphology and locomotion. Vinculin is expressed in the muscles. Mutations in the VCL gene may result in cardiomyopathy. STJ96247 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Vinculin protein.
- 特异性
- Vinculin Polyclonal Antibody detects endogenous levels of Vinculin protein.
- 产品特性
- Rabbit polyclonal to Vinculin.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from human Vinculin around the non-phosphorylation site of Y821.
- 亚型
- IgG
- Top Product
- Discover our top product VCL Primary Antibody
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- 应用备注
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WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000 - 说明
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Metavinculin is muscle-specific.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- 抗原
- Vinculin (VCL)
- 别名
- Vinculin (VCL 产品)
- 别名
- CMD1W antibody, CMH15 antibody, MV antibody, MVCL antibody, VCL antibody, im:6902790 antibody, hm:zehn2160 antibody, DDBDRAFT_0186762 antibody, DDBDRAFT_0232320 antibody, DDB_0186762 antibody, DDB_0232320 antibody, 9430097D22 antibody, AA571387 antibody, AI462105 antibody, AW545629 antibody, CG3299 antibody, CT11081 antibody, Dmel\\CG3299 antibody, Dmvincp antibody, EG:103B4.1 antibody, Vin antibody, Vin2EF antibody, vinc antibody, LOC100228062 antibody, vcl-A antibody, vinculin antibody, vinculin a antibody, vinculin A antibody, Vinculin antibody, vinculin S homeolog antibody, VCL antibody, vcla antibody, vinA antibody, Vcl antibody, Vinc antibody, CpipJ_CPIJ013873 antibody, Bm1_37935 antibody, vcl antibody, vcl.S antibody
- 分子量
- 123 kDa
- 基因ID
- 7414
- UniProt
- P18206
- 途径
- Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
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