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CEP290 抗体 (Internal Region)

CEP290 适用: 人, 小鼠 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6284993
发货至: 中国
  • 抗原 See all CEP290 抗体
    CEP290 (Centrosomal Protein 290kDa (CEP290))
    抗原表位
    • 15
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 740-820, Internal Region
    适用
    • 28
    • 24
    • 3
    • 1
    • 1
    人, 小鼠
    宿主
    • 41
    • 2
    克隆类型
    • 43
    多克隆
    标记
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This CEP290 antibody is un-conjugated
    应用范围
    • 15
    • 14
    • 13
    • 13
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    ELISA, Western Blotting (WB), Immunofluorescence (IF)
    原理
    CEP290 is a protein encoded by the CEP290 gene which is approximately 290,3 kDa. CEP290 is localised to the cytoplasm. It is involved in regulation of PLK1 activity at G2/M transition, innate immune system and mitotic cell cycle. It is a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. It is involved in the early and late steps of cilia formation. CEP290 is ubiquitously expressed with stronger expression in the placenta. Mutations in the CEP290 gene may result in Joubert syndrome. STJ92224 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of CEP290 protein.
    特异性
    CEP290 Polyclonal Antibody detects endogenous levels of CEP290 protein.
    产品特性
    Rabbit polyclonal to CEP290.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    Synthesized peptide derived from human CEP290
    亚型
    IgG
    Top Product
    Discover our top product CEP290 Primary Antibody
  • 应用备注
    WB 1:500-1:2000
    ELISA 1:20000
    说明

    Ubiquitous. Expressed strongly in placenta and weakly in brain.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • 抗原
    CEP290 (Centrosomal Protein 290kDa (CEP290))
    别名
    CEP290 (CEP290 产品)
    别名
    ct87 antibody, mks4 antibody, rd16 antibody, bbs14 antibody, jbts5 antibody, jbts6 antibody, lca10 antibody, nphp6 antibody, slsn6 antibody, sh11ag antibody, MGC81471 antibody, 3h11ag antibody, RGD1311640 antibody, BC004690 antibody, Nphp6 antibody, b2b1454Clo antibody, b2b1752Clo antibody, im:7145703 antibody, im:7147820 antibody, 3H11Ag antibody, BBS14 antibody, CT87 antibody, JBTS5 antibody, LCA10 antibody, MKS4 antibody, NPHP6 antibody, POC3 antibody, SLSN6 antibody, centrosomal protein 290 antibody, centrosomal protein 290 L homeolog antibody, centrosomal protein 290kDa antibody, CEP290 antibody, cep290.L antibody, cep290 antibody, Cep290 antibody
    分子量
    290 kDa
    基因ID
    80184
    UniProt
    O15078
    途径
    cAMP Metabolic Process, M Phase
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