PKC 抗体 (AA 600-680)
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- 抗原 See all PKC (PKC pan) 抗体
- PKC (PKC pan) (Protein Kinase C (pan) (PKC pan))
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抗原表位
- AA 600-680
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PKC antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- PKC is a protein encoded by the PRKCA gene which is approximately 76,7 kDa. PKC is localised to the cytoplasm and cell membrane. It is involved in RET signalling, DAG and IP3 signalling, the IL-2 Pathway, fMLP pathway and CDK-mediated phosphorylation and removal of Cdc6. It is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. It plays a role in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. PKC is expressed in the liver, blood, nervous system, skin and pancreas. Mutations in the PRKCA gene may result in glioma and myotonic dystrophy. STJ95117 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of PKC protein.
- 特异性
- PKC Polyclonal Antibody detects endogenous levels of PKC protein.
- 产品特性
- Rabbit polyclonal to PKC.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from human PKC around the non-phosphorylation site of T497.
- 亚型
- IgG
- Top Product
- Discover our top product PKC pan Primary Antibody
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- 应用备注
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WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:5000 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- 抗原
- PKC (PKC pan) (Protein Kinase C (pan) (PKC pan))
- 别名
- PKC (PKC pan 产品)
- 别名
- PKC antibody, PKCI antibody, Prkc antibody, Prkcc antibody, RATPKCI antibody, protein kinase C, gamma antibody, Prkcg antibody
- 分子量
- 85 kDa
- 基因ID
- 5578
- UniProt
- P17252
- 途径
- Positive Regulation of Response to DNA Damage Stimulus
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