Kv2.1/KCNB1 抗体 (AA 510-590)
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- 抗原 See all Kv2.1/KCNB1 (KCNB1) 抗体
- Kv2.1/KCNB1 (KCNB1) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 1 (KCNB1))
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抗原表位
- AA 510-590
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Kv2.1/KCNB1 antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Kv2.1 is a protein encoded by the KCNB1 gene which is approximately 95,8 kDa. Kv2.1 is localised to the cell membrane. It is involved in integration of energy metabolism, potassium channels and aquaporin-mediated transport. It contributes to the regulation of the action potential (AP) repolarization, duration and frequency of repetitive AP firing in neurons, muscle cells and endocrine cells and also plays a role in homeostatic attenuation of electrical excitability throughout the brain. Kv2.1 is expressed in the brain, heart, lung, liver, colon, kidney and adrenal gland. Mutations in the KCNB1 gene may result in epileptic encephalopathy. STJ93873 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Kv2.1 protein.
- 特异性
- Kv2.1 Polyclonal Antibody detects endogenous levels of Kv2.1 protein.
- 产品特性
- Rabbit polyclonal to Kv2.1.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from human Kv2.1 around the non-phosphorylation site of S567.
- 亚型
- IgG
- Top Product
- Discover our top product KCNB1 Primary Antibody
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- 应用备注
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IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000 - 说明
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Expressed in neocortical pyramidal cells . Expressed in pancreatic beta cells (at protein level) . Expressed in brain, heart, lung, liver, colon, kidney and adrenal gland . Expressed in the cortex, amygdala, cerebellum, pons, thalamus, hypothalamus, hippocampus and substantia nigra .
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- 抗原
- Kv2.1/KCNB1 (KCNB1) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 1 (KCNB1))
- 别名
- Kv2.1 (KCNB1 产品)
- 别名
- KCNB1 antibody, Kcnb1 antibody, Kcr1-1 antibody, Kv2.1 antibody, Shab antibody, DRK1PC antibody, DRK1 antibody, KV2.1 antibody, h-DRK1 antibody, potassium voltage-gated channel subfamily B member 1 antibody, potassium voltage-gated channel, Shab-related subfamily, member 1 antibody, potassium channel, voltage gated Shab related subfamily B, member 1 antibody, potassium voltage gated channel, Shab-related subfamily, member 1 antibody, KCNB1 antibody, kcnb1 antibody, LOC100541632 antibody, Kcnb1 antibody
- 分子量
- 90 kDa
- 基因ID
- 3745
- UniProt
- Q14721
- 途径
- Synaptic Membrane
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