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BMP2 抗体 (C-Term)

BMP2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6283442
发货至: 中国
  • 抗原 See all BMP2 抗体
    BMP2 (Bone Morphogenetic Protein 2 (BMP2))
    抗原表位
    • 15
    • 15
    • 15
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 341-390, C-Term
    适用
    • 93
    • 48
    • 48
    • 22
    • 16
    • 14
    • 12
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 109
    • 19
    • 6
    • 1
    克隆类型
    • 118
    • 17
    多克隆
    标记
    • 63
    • 26
    • 12
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This BMP2 antibody is un-conjugated
    应用范围
    • 126
    • 51
    • 45
    • 26
    • 26
    • 19
    • 18
    • 14
    • 12
    • 11
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    • 7
    • 6
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    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    BMP-2 is a protein encoded by the BMP2 gene which is approximately 44,7 kDa. BMP-2 is secreted into the extracellular space. It is involved in apoptotic pathways, PEDF induced signalling, the GPCR pathway and ERK signalling. This protein is a secreted ligand of the TGF-beta superfamily of proteins. It binds various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. It is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. BMP-2 is expressed in the bone, muscle, bone marrow, nervous system and lung. Mutations in the BMP2 gene may result in Cauda Equina syndrome. STJ97346 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of BMP-2 protein.
    特异性
    BMP-2 Polyclonal Antibody detects endogenous levels of BMP-2 protein.
    产品特性
    Rabbit polyclonal to BMP-2.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    Synthesized peptide derived from human BMP-2.
    亚型
    IgG
    Top Product
    Discover our top product BMP2 Primary Antibody
  • 应用备注
    WB 1:500-1:2000
    IHC-P 1:100-1:300
    ELISA 1:10000
    说明

    Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • 抗原
    BMP2 (Bone Morphogenetic Protein 2 (BMP2))
    别名
    BMP-2 (BMP2 产品)
    别名
    BDA2 antibody, BMP2A antibody, AI467020 antibody, Bmp2a antibody, BMP-2 antibody, xBMP-2 antibody, xbmp2 antibody, BMP2 antibody, bmp2a antibody, bmp2 antibody, wu:fc59d09 antibody, bone morphogenetic protein 2 antibody, bone morphogenetic protein 2 L homeolog antibody, Bone morphogenetic protein 2 antibody, bone morphogenetic protein 2a antibody, BMP2 antibody, Bmp2 antibody, bmp2.L antibody, bmp2 antibody, bmp2a antibody
    基因ID
    650
    UniProt
    P12643
    途径
    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation
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