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PPP1CA 抗体 (pThr320)

PPP1CA 适用: 人, 小鼠, 大鼠 ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6282675
发货至: 中国
  • 抗原 See all PPP1CA 抗体
    PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))
    抗原表位
    • 12
    • 10
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 260-340, pThr320
    适用
    • 74
    • 41
    • 40
    • 16
    • 10
    • 7
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 49
    • 24
    • 2
    • 1
    克隆类型
    • 52
    • 24
    多克隆
    标记
    • 54
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This PPP1CA antibody is un-conjugated
    应用范围
    • 50
    • 26
    • 16
    • 12
    • 10
    • 10
    • 10
    • 3
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    PP1α is a protein encoded by the PPP1CA gene which is approximately 37,5 kDa. PP1α is localised to the cytoplasm and nucleus. It is involved in vascular smooth muscle contraction, regulation of lipid metabolism and insulin signalling-generic cascades. It is one of the three catalytic subunits of protein phosphatase 1. It is an enzyme that catalyses the removal of phosphate groups from serine and/or threonine residues by hydrolysis of phosphoric acid monoesters. They oppose the action of kinases and phosphorylases and are involved in signal transduction. PP1α is expressed in the lung, muscle, blood, pancreas and liver. Increased activity of this protein has been observed in the end stage of heart failure. STJ91134 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody specifically binds to endogenous PP1α protein which only binds about T320 when T320 is phosphorylated.
    特异性
    Phospho-PP1α (T320) Polyclonal Antibody detects endogenous levels of PP1α protein only when phosphorylated at T320.
    产品特性
    Rabbit polyclonal to Phospho-PP1α (T320).
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    Synthesized peptide derived from human PP1alpha around the phosphorylation site of T320.
    亚型
    IgG
    Top Product
    Discover our top product PPP1CA Primary Antibody
  • 应用备注
    IHC 1:100-1:300
    ELISA 1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • 抗原
    PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))
    别名
    PP1alpha (PPP1CA 产品)
    别名
    PP-1A antibody, PP1A antibody, PP1alpha antibody, PPP1A antibody, Ppp1c antibody, dism2 antibody, ppp1a antibody, wu:fc04c08 antibody, wu:fc09b07 antibody, wu:fc30g11 antibody, wu:fe05h08 antibody, zgc:85729 antibody, Ppp1ca antibody, fb18b03 antibody, fd20h04 antibody, wu:fb18b03 antibody, wu:fd20h04 antibody, wu:fl22a03 antibody, zgc:55744 antibody, zgc:76940 antibody, protein phosphatase 1 catalytic subunit alpha antibody, protein phosphatase 1, catalytic subunit, alpha isoform antibody, protein phosphatase 1, catalytic subunit, alpha isozyme L homeolog antibody, protein phosphatase 1, catalytic subunit, alpha isozyme antibody, protein phosphatase 1, catalytic subunit, alpha isozyme a antibody, protein phosphatase 1, catalytic subunit, alpha isozyme b antibody, PPP1CA antibody, Ppp1ca antibody, ppp1ca.L antibody, ppp1ca antibody, ppp1caa antibody, ppp1cab antibody
    分子量
    37 kDa
    基因ID
    5499
    UniProt
    P62136
    途径
    M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism
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