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Cytokeratin 19 抗体 (Internal Region)

KRT19 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6282124
发货至: 中国
  • 抗原 See all Cytokeratin 19 (KRT19) 抗体
    Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))
    抗原表位
    • 19
    • 16
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    AA 200-280, Internal Region
    适用
    • 253
    • 88
    • 70
    • 7
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    • 2
    • 2
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    • 1
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    人, 小鼠, 大鼠
    宿主
    • 134
    • 129
    • 3
    • 1
    • 1
    克隆类型
    • 139
    • 129
    多克隆
    标记
    • 117
    • 33
    • 19
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    This Cytokeratin 19 antibody is un-conjugated
    应用范围
    • 184
    • 93
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    • 33
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    • 21
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    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Cytokeratin 19 is a protein encoded by the KRT19 gene which is approximately 44,1 kDa. Cytokeratin 19 is localised to the cytosol. It is involved in cytoskeletal signalling, developmental biology and keratinization. This protein falls under the keratin family and consists of acidic proteins which are arranged in pairs of heterotypic keratin chains. It plays a role in the organization of myofibers and together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. Cytokeratin 19 is expressed in basal keratinocytes in the deep outer root sheath of hair follicles. Mutations in the KRT19 gene may result in lung cancer and thyroid cancer. STJ92634 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Cytokeratin 19 protein.
    特异性
    Cytokeratin 19 Polyclonal Antibody detects endogenous levels of Cytokeratin 19 protein.
    产品特性
    Rabbit polyclonal to Cytokeratin 19.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    Synthesized peptide derived from human Cytokeratin 19
    亚型
    IgG
    Top Product
    Discover our top product KRT19 Primary Antibody
  • 应用备注
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:10000
    说明

    Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • 抗原
    Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))
    别名
    Cytokeratin 19 (KRT19 产品)
    别名
    CK19 antibody, K19 antibody, K1CS antibody, AI663979 antibody, EndoC antibody, Krt-1.19 antibody, Krt1-19 antibody, Ka19 antibody, k19 antibody, ck19 antibody, k1cs antibody, krt9 antibody, krt15 antibody, MGC76282 antibody, GK-19 antibody, MGC83069 antibody, KRT19 antibody, keratin 19 antibody, keratin 19 L homeolog antibody, keratin, type I cytoskeletal 19 antibody, KRT19 antibody, Krt19 antibody, krt19 antibody, krt19.L antibody, LOC100344434 antibody, LOC101117946 antibody
    分子量
    45 kDa
    基因ID
    3880
    UniProt
    P08727
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