MARK1/2/3/4 抗体 (AA 150-230)
-
- 抗原 See all MARK1/2/3/4 products
- MARK1/2/3/4 (MAP/microtubule Affinity-Regulating Kinase 1/2/3/4 (MARK1/2/3/4))
-
抗原表位
- AA 150-230
-
适用
- 人, 小鼠, 大鼠, 猴
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This MARK1/2/3/4 antibody is un-conjugated
-
应用范围
- ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- MARK1/2/3/4 is a protein encoded by the MARK1 gene which is approximately 89 kDa. MARK1/2/3/4 is localised to the cell membrane and cytoplasm. It is involved in cytoplasm signalling and glucose/energy metabolism. It plays a role in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. MARK1/2/3/4 is highly expressed in the heart, skeletal muscle, brain and foetal kidney. Mutations in the MARK1 gene may result in Alzheimer disease. STJ94015 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of MARK1/2/3/4 protein.
- 特异性
- MARK1/2/3/4 Polyclonal Antibody detects endogenous levels of MARK1/2/3/4 protein.
- 产品特性
- Rabbit polyclonal to MARK1/2/3/4.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from human MARK1/2/3/4 around the non-phosphorylation site of T215.
- 亚型
- IgG
-
anti-MAP/microtubule Affinity-Regulating Kinase 1/2/3/4 (MARK1/2/3/4) (AA 181-230) antibody
MARK1/2/3/4 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-MAP/microtubule Affinity-Regulating Kinase 1/2/3/4 (MARK1/2/3/4) (Internal Region) antibodyMARK1/2/3/4 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-MAP/microtubule Affinity-Regulating Kinase 1/2/3/4 (MARK1/2/3/4) (Lys16) antibodyMARK1/2/3/4 适用: 人, 小鼠, 大鼠, 猴 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-MAP/microtubule Affinity-Regulating Kinase 1/2/3/4 (MARK1/2/3/4) (AA 121-170) antibodyMARK1/2/3/4 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000 - 说明
-
Highly expressed in heart, skeletal muscle, brain, fetal brain and fetal kidney.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
-
- 抗原
- MARK1/2/3/4 (MAP/microtubule Affinity-Regulating Kinase 1/2/3/4 (MARK1/2/3/4))
- 别名
- MARK1/2/3/4 (MARK1/2/3/4 产品)
- 分子量
- 89 kDa
- 基因ID
- 4139
- UniProt
- Q9P0L2
-
