RIP2 抗体 (pSer176)
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- 抗原 See all RIP2 抗体
- RIP2 (ROP Interactive Partner 2 (RIP2))
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抗原表位
- AA 120-200, pSer176
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RIP2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- RIP2 is a protein encoded by the RIPK2 gene which is approximately 61,2 kDa. RIP2 is localised to the cytoplasm. It is involved in activated TLR4 signalling, p75 NTR receptor-mediated signalling, toll-like receptor signalling pathways and cytokine signalling in immune system. It is a serine/threonine/tyrosine kinase that contains a C-terminal caspase activation and recruitment domain and plays an essential role in modulation of innate and adaptive immune responses. RIP2 is expressed in the heart, brain, placenta, lung, peripheral blood leukocytes, spleen and kidney. Mutations in the RIPK2 gene may result in x-linked lymphoproliferative syndrome and human granulocytic anaplasmosis. STJ90957 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody specifically binds to endogenous RIP2 protein which only binds about S176 when S176 is phosphorylated.
- 特异性
- Phospho-RIP2 (S176) Polyclonal Antibody detects endogenous levels of RIP2 protein only when phosphorylated at S176.
- 产品特性
- Rabbit polyclonal to Phospho-RIP2 (S176).
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from human RIP2 around the phosphorylation site of S176.
- 亚型
- IgG
- Top Product
- Discover our top product RIP2 Primary Antibody
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anti-ROP Interactive Partner 2 (RIP2) (AA 401-540) antibody
RIP2 适用: 人, 小鼠 WB, ELISA, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-ROP Interactive Partner 2 (RIP2) (AA 1-322) antibodyRIP2 适用: 人 WB 宿主: 大鼠 Monoclonal Nick-1 unconjugated
anti-ROP Interactive Partner 2 (RIP2) (pSer176) antibodyRIP2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ROP Interactive Partner 2 (RIP2) (Tyr397) antibodyRIP2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ROP Interactive Partner 2 (RIP2) (N-Term) antibodyRIP2 适用: 人, 小鼠, 大鼠 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-ROP Interactive Partner 2 (RIP2) (C-Term) antibodyRIP2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-ROP Interactive Partner 2 (RIP2) (Ser176) antibodyRIP2 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000 - 说明
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Detected in heart, brain, placenta, lung, peripheral blood leukocytes, spleen, kidney, testis, prostate, pancreas and lymph node.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- 抗原
- RIP2 (ROP Interactive Partner 2 (RIP2))
- 别名
- RIP2 (RIP2 产品)
- 分子量
- 70 kDa
- 基因ID
- 8767
- UniProt
- O43353
- 途径
- TCR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades
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