PDX1 抗体 (Internal Region)
(1 reference)-
- 抗原 See all PDX1 抗体
- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PDX1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- PDX1 Antibody detects endogenous levels of total PDX1.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human PDX1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product PDX1 Primary Antibody
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anti-Pancreatic and Duodenal Homeobox 1 (PDX1) (AA 1-284) antibody
PDX1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pancreatic and Duodenal Homeobox 1 (PDX1) antibodyPDX1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2G12 unconjugated
anti-Pancreatic and Duodenal Homeobox 1 (PDX1) (AA 1-30) antibodyPDX1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pancreatic and Duodenal Homeobox 1 (PDX1) antibodyPDX1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pancreatic and Duodenal Homeobox 1 (PDX1) (AA 1-283) antibodyPDX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Pancreatic and Duodenal Homeobox 1 (PDX1) (AA 1-30) antibodyPDX1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB15204 unconjugated
anti-Pancreatic and Duodenal Homeobox 1 (PDX1) antibodyPDX1 适用: 人 WB, FACS, EIA 宿主: 小鼠 Monoclonal 5A5 unconjugated
anti-Pancreatic and Duodenal Homeobox 1 (PDX1) (AA 188-284) antibodyPDX1 适用: 大鼠, 山羊 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Pancreatic and Duodenal Homeobox 1 (PDX1) (AA 136-169) antibodyPDX1 适用: 小鼠 WB, IF 宿主: 兔 Polyclonal RB51197 unconjugated
anti-Pancreatic and Duodenal Homeobox 1 (PDX1) (AA 109-208) antibodyPDX1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4E12 unconjugated
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- 应用备注
- WB 1:500-1:1000, IHC 1:50-1:100, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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: "Sall2 knockdown exacerbates palmitic acid induced dysfunction and apoptosis of pancreatic NIT-1 beta cells." in: Biomedicine & pharmacotherapy, Vol. 104, pp. 375-382, (2018) (PubMed).
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: "Sall2 knockdown exacerbates palmitic acid induced dysfunction and apoptosis of pancreatic NIT-1 beta cells." in: Biomedicine & pharmacotherapy, Vol. 104, pp. 375-382, (2018) (PubMed).
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- 抗原
- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
- 别名
- PDX1 (PDX1 产品)
- 别名
- GSF antibody, IDX-1 antibody, IPF1 antibody, IUF1 antibody, MODY4 antibody, PDX-1 antibody, STF-1 antibody, ipf1 antibody, PDX1 antibody, IPF-1 antibody, Ipf1 antibody, Mody4 antibody, pdx-1 antibody, Idx1 antibody, Stf1 antibody, zgc:100874 antibody, XlHbox-8 antibody, xlhbox8 antibody, pancreatic and duodenal homeobox 1 antibody, pancreatic and duodenal homeobox 1 S homeolog antibody, PDX1 antibody, pdx1 antibody, Pdx1 antibody, pdx1.S antibody
- 背景
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Description: Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer, the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, required for maintaining the hormone-producing phenotype of the beta-cell.
Gene: PDX1
- 分子量
- 31kDa
- 基因ID
- 3651
- UniProt
- P52945
- 途径
- Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
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